Vishnevetskiĭ F E, Freĭdlin I S, Iushchenko A A, Vishnevetskiĭ R F, Anokhina V V, Urliapova N G, Iushin M Iu, Eskina I M
Biull Eksp Biol Med. 1991 Aug;112(8):181-3.
The effect of tuftsin was studied in vivo using CBA mice infected with M. leprae by Shepard's technique and in vitro using macrophage-like cell line P. 388 (Co-cultivated with M. leprae) and the cultivated leproma tissue. It was found out that tuftsin acted as a stimulator of M. leprae multiplication in foot-pads of mice and as a prolongator of M. leprae survival in the cells of macrophage-like cell line P .388. It is concluded that using tuftsin might be useful in view of studying different aspects of experimental leprosy.
使用谢泼德技术感染麻风杆菌的CBA小鼠在体内研究了促吞噬素的作用，并在体外使用巨噬细胞样细胞系P. 388（与麻风杆菌共培养）和培养的瘤型麻风组织进行了研究。结果发现，促吞噬素在小鼠足垫中可作为麻风杆菌增殖的刺激物，在巨噬细胞样细胞系P. 388的细胞中可作为麻风杆菌存活的延长剂。得出的结论是，鉴于研究实验性麻风病的不同方面，使用促吞噬素可能是有用的。
