Guinto R S, Cellona R V, Fajardo T T, de la Cruz E C
Int J Lepr Other Mycobact Dis. 1981 Dec;49(4):427-30.
A survey of the prevalence of primary dapsone-resistant leprosy in Cebu, Philippines, has yielded an estimate of 3.6 per 100. Fifty-three of 55 patients proved to have M. leprae fully susceptible to dapsone. The organisms of two patients multiplied in mice administered the minimal effective dose of dapsone; and those of one of these patients also multiplied in mice administered dapsone in a 10-fold larger dose.