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Primary dapsone-resistant leprosy in Cebu, Philippines.

作者信息

Guinto R S, Cellona R V, Fajardo T T, de la Cruz E C

出版信息

Int J Lepr Other Mycobact Dis. 1981 Dec;49(4):427-30.

PMID:7042607
Abstract

A survey of the prevalence of primary dapsone-resistant leprosy in Cebu, Philippines, has yielded an estimate of 3.6 per 100. Fifty-three of 55 patients proved to have M. leprae fully susceptible to dapsone. The organisms of two patients multiplied in mice administered the minimal effective dose of dapsone; and those of one of these patients also multiplied in mice administered dapsone in a 10-fold larger dose.

摘要

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