Kul'bakh O S
Arkh Anat Gistol Embriol. 1984 Apr;86(4):39-45.
The dynamic of cellular reactions demonstrates certain changes in functional activity of all structures of the node during pregnancy. A similar trend of processes in the iliac (regional for the uterus) and mesenteric lymph nodes has been defined. At early stages of pregnancy, lymph nodule are the most active, this is demonstrated as an increasing portion of lymphoblasts, macrophages and dividing cells. During this period, cell composition of the cortical plateau is relatively stable. For the paracortical zone of the mesenteric lymph nodes a rather significant decrease in the portion of middle lymphocytes and reticular cells is characteristic. There is not any significant change in the relative amount of the cells in the same functional zone of the iliac lymph nodes during the same period of pregnancy. The medullar cords demonstrate an increasing number of blast forms and young plasmocytes. However, as the pregnancy develops, the structure of the paracortical zone undergoes an essential change--progressively increases the portion of lymphoblasts and large lymphocytes. The blastic reaction in the mesenteric lymph nodes is proved to depend, to some extent, on that in the iliac lymph nodes of the same animal. Mature plasma cells become the dominating cellular element in the medullary cords. At the end of the pregnancy a relative amount of the reticular cells increases in all structural zones of the node.
细胞反应的动态变化表明,孕期淋巴结所有结构的功能活性会发生某些改变。已确定在髂(子宫区域)淋巴结和肠系膜淋巴结中存在类似的过程趋势。在妊娠早期,淋巴小结最为活跃,表现为成淋巴细胞、巨噬细胞和分裂细胞的比例增加。在此期间,皮质高原的细胞组成相对稳定。肠系膜淋巴结副皮质区的特征是中淋巴细胞和网状细胞的比例显著下降。在同一孕期,髂淋巴结相同功能区的细胞相对数量没有任何显著变化。髓索中母细胞样形态和年轻浆细胞的数量增加。然而,随着妊娠进展,副皮质区的结构发生了本质变化——成淋巴细胞和大淋巴细胞的比例逐渐增加。事实证明,肠系膜淋巴结中的母细胞反应在一定程度上取决于同一动物髂淋巴结中的反应。成熟浆细胞成为髓索中占主导地位的细胞成分。在妊娠末期,淋巴结所有结构区的网状细胞相对数量增加。