Niers Laetitia, Stasse-Wolthuis Marianne, Rombouts Frans M, Rijkers Ger T
Department of Pediatrics, Wilhelmina Children's Hospital, University Medical Center, Utrecht, The Netherlands.
Nutr Rev. 2007 Aug;65(8 Pt 1):347-60. doi: 10.1301/nr.2007.aug.347-360.
Newborn babies possess a functional but immature immune system as a defense against a world teeming with microorganisms. Breast milk contains a number of biological, active compounds that support the infant's immune system. These include secretory immunoglobulin A (IgA), which confers specific protection against enteric pathogens, as well as numerous other immunological, active ingredients. A number of these ingredients can be used as supplements for infant formulas based on cow's milk. Here, the strength of evidence regarding the immune-stimulating effects of selected minerals, vitamins, fatty acids, pre- and probiotics, and nucleotides is reviewed. An assessment of how these ingredients are used in infant-formula products currently available on the market is also presented.
新生儿拥有一个功能正常但尚未成熟的免疫系统，以抵御充满微生物的世界。母乳含有多种支持婴儿免疫系统的生物活性化合物。这些包括分泌型免疫球蛋白A（IgA），它能对肠道病原体提供特异性保护，以及许多其他免疫活性成分。其中一些成分可作为以牛奶为基础的婴儿配方奶粉的补充剂。在此，我们综述了关于特定矿物质、维生素、脂肪酸、益生元和益生菌以及核苷酸的免疫刺激作用的证据强度。同时还对这些成分在目前市场上可得的婴儿配方奶粉产品中的使用情况进行了评估。
