Solaro Claudio, Tanganelli Paolo, Messmer Uccelli Michele
ASL 3 Hospitals, Department of Neurology, Via Oliva 22, Genoa 16153, Italy.
Expert Rev Neurother. 2007 Sep;7(9):1165-74. doi: 10.1586/14737175.7.9.1165.
Pain is a common symptom in multiple sclerosis (MS) and was recently estimated to be experienced by up to 75% of patients. Nociceptive and neuropathic pain in MS may be present concurrently and at different stages of the disease and may be associated with other symptoms. Evidence for treating pain in MS is limited. Many clinical features of pain are often unrecognized by clinicians and are difficult for patients to describe. Treatment is often based on anecdotal reports and clinical experience. We present a review of treatment options for pain in MS that should serve to update current knowledge, highlight shortcomings in clinical research and provide indications towards achieving evidence-based treatment of pain in MS.
疼痛是多发性硬化症（MS）的常见症状，最近估计高达75%的患者会经历疼痛。MS中的伤害性疼痛和神经性疼痛可能同时存在于疾病的不同阶段，并且可能与其他症状相关。治疗MS疼痛的证据有限。疼痛的许多临床特征往往未被临床医生识别，患者也难以描述。治疗通常基于轶事报道和临床经验。我们对MS疼痛的治疗选择进行了综述，旨在更新当前知识，突出临床研究中的不足，并为实现MS疼痛的循证治疗提供指导。
