Litvinova S V, Aristova V V, Kaliuzhnyĭ A L, Shul'govskiĭ V V, Kaliuzhnyĭ L V
Farmakol Toksikol. 1991 Jul-Aug;54(4):13-5.
In experiments of albino rats neurotropin injection was shown to increase the latency of the tail-flick test in response to the nociceptive thermal stimulus and didn't change the threshold of the test in response to the nociceptive electroskin stimulus. The administration of the antiserum to beta-endorphin lowered the threshold and the latency of the tail-flick test in response to both stimuli. The preliminary administration of neurotropin reduced the hyperalgesic effect of the antiserum on both nociceptive stimuli.
在对白化大鼠的实验中，结果显示注射神经妥乐平可增加甩尾试验对伤害性热刺激的反应潜伏期，且不改变该试验对伤害性皮肤电刺激的阈值。给予β-内啡肽抗血清会降低对两种刺激的甩尾试验阈值和潜伏期。预先注射神经妥乐平可减轻抗血清对两种伤害性刺激的痛觉过敏作用。
