Ignatov Iu D, Zaĭtsev A A, Abdrakhmanov A A
Farmakol Toksikol. 1990 Nov-Dec;53(6):17-9.
The ionizing radiation (150 Gy) extended the rat tail flick latency, decreased the pain-relief effects of morphine and opioids and enhanced the analgesic effect of clopheline. The radiation was followed by a decrease of vocalization threshold with a reduction of morphine- and clopheline-induced analgesia. Naloxone (0.1 mg/kg) eliminated the postradiation analgesia and did not change the hyperalgesic effect of the radiation.
电离辐射（150 Gy）延长了大鼠的甩尾潜伏期，降低了吗啡和阿片类药物的镇痛效果，并增强了氯苯乙脒的镇痛作用。辐射后，发声阈值降低，同时吗啡和氯苯乙脒诱导的镇痛作用减弱。纳洛酮（0.1 mg/kg）消除了辐射后的镇痛作用，且未改变辐射的痛觉过敏效应。
