Keel Pamela K
Department of Psychology, The University of Iowa, Iowa City 52242, USA.
Int J Eat Disord. 2007 Nov;40 Suppl:S89-94. doi: 10.1002/eat.20453.
To review evidence of the clinical significance, distinctiveness, and prevalence of a newly characterized form of eating disorder not otherwise specified, purging disorder (PD).
Articles were identified by computerized and manual searches.
PD is a clinically significant disorder of eating that does not appear to differ meaningfully in severity from bulimia nervosa (BN). Preliminary evidence supports the distinctiveness of PD from BN, but no studies have directly examined PD in comparison with anorexia nervosa (AN). Epidemiological studies indicate that PD affects between 1.1 and 5.3% of young adult women in their lifetimes, reflecting lifetime prevalence rates comparable with those for AN and BN.
More research on PD is needed, particularly with regard to etiology, treatment, course, and outcome. Such work would be greatly facilitated by standardization of the syndrome's definition.
回顾一种新定义的未另行规定的饮食失调形式——清除障碍（PD）的临床意义、独特性及患病率的相关证据。
通过计算机检索和人工检索确定文章。
PD是一种具有临床意义的饮食障碍，其严重程度似乎与神经性贪食症（BN）并无显著差异。初步证据支持PD与BN的独特性，但尚无研究将PD与神经性厌食症（AN）进行直接对比。流行病学研究表明，PD在成年女性一生中的影响率为1.1%至5.3%，反映出其终生患病率与AN和BN相当。
需要对PD开展更多研究，尤其是在病因、治疗、病程和转归方面。综合征定义的标准化将极大推动此类研究工作。
