Roussin Anne, Montastruc Jean-Louis, Lapeyre-Mestre Maryse
Service de Pharmacologie Clinique, Centre d'Evaluation et d'Information sur la Pharmacodépendance de Toulouse, EA 3696, Université Paul Sabatier, Faculté de Médecine, 31000 Toulouse, France.
Fundam Clin Pharmacol. 2007 Oct;21(5):459-66. doi: 10.1111/j.1472-8206.2007.00497.x.
Propofol (2,6-diisopropylphenol) is an intravenous short-acting anaesthetic widely used for inducing and maintaining anaesthesia. Propofol is also being increasingly used for sedation. Beside medical use, propofol is abused for recreational purpose, mostly in medical professionals who are not informed of the risk of dependence to this compound. The aim of this review was to provide an overview of molecular, animal and clinical pharmacological data of the literature evidencing the potential for abuse and dependence of propofol.
丙泊酚（2,6 - 二异丙基苯酚）是一种静脉注射用短效麻醉剂，广泛用于诱导和维持麻醉。丙泊酚也越来越多地用于镇静。除医疗用途外，丙泊酚还被滥用于娱乐目的，主要是在未被告知该化合物成瘾风险的医疗专业人员中。本综述的目的是概述文献中的分子、动物和临床药理学数据，以证明丙泊酚存在滥用和成瘾的可能性。
