Motamedi Gholam K, Okunola Oladotun, Kalhorn Christopher G, Mostofi Navid, Mizuno-Matsumoto Yuko, Cho Yong-Won, Meador Kimford J
Department of Neurology, PHC 7, Georgetown University Hospital, 3800 Reservior Rd., NW, Washington, DC 20007, USA.
Epilepsy Res. 2007 Oct;77(1):65-9. doi: 10.1016/j.eplepsyres.2007.08.001. Epub 2007 Sep 14.
The occurrence of unwanted afterdischarges (ADs) impedes cortical stimulation for mapping purposes. We investigated the safety of several stimulation paradigms.
We compared the incidence of ADs and behavioral responses of two stimulation frequencies (50 and 100 Hz), at two intensities (1 and 0.2 ms pulse widths).
Stimulation with 100 Hz was more likely to cause ADs than 50 Hz, and stimulation using 1 ms pulse width was more likely to cause ADs than 0.2 ms.
Stimulation using 50 Hz frequency with a pulse width of 0.2 ms might be safer during cortical mapping.
不必要的后放电(ADs)的出现妨碍了用于图谱绘制的皮层刺激。我们研究了几种刺激模式的安全性。
我们比较了两种刺激频率(50和100赫兹)、两种强度(1和0.2毫秒脉冲宽度)下ADs的发生率和行为反应。
100赫兹的刺激比50赫兹更易引发ADs,1毫秒脉冲宽度的刺激比0.2毫秒更易引发ADs。
在皮层图谱绘制过程中,使用50赫兹频率和0.2毫秒脉冲宽度的刺激可能更安全。