Diehl L F
Department of Medicine, Walter Reed Army Medical Center, Washington, DC.
Gastroenterol Clin North Am. 1991 Dec;20(4):765-74.
Patients with esophageal cancer present with a cancer that is locally aggressive in a critical area and that readily metastasizes. Neither surgery nor radiotherapy alone can control local disease, and chemotherapy alone cannot control local or disseminated disease. Combined modalities yield better results. Surgery or radiotherapy is the standard primary treatment. Chemotherapy may help to control local disease and microscopic metastatic disease. Prospective randomized trials indicate that chemotherapy added to surgery and radiotherapy and chemotherapy added to radiotherapy prolong survival.
食管癌患者所患癌症在关键区域具有局部侵袭性且易于转移。单独手术或放疗都无法控制局部疾病，单独化疗也无法控制局部或播散性疾病。联合治疗方式能产生更好的效果。手术或放疗是标准的主要治疗方法。化疗可能有助于控制局部疾病和微小转移病灶。前瞻性随机试验表明，手术及放疗联合化疗以及放疗联合化疗可延长生存期。
