Herrmann R
Abteilung für Onkologie, Kantonsspital Basel.
Schweiz Med Wochenschr. 1993 May 29;123(21):1103-5.
In metastatic esophageal cancer, single agent or combination chemotherapy induces short remissions in only a minority of patients. Therefore, only selected patients should be treated. More than half of patients with locoregional disease will experience significant improvement through cisplatinum-based combination chemotherapy. However, this has so far not shown itself to influence overall survivaL. Combination chemo-radiotherapy is superior to radiotherapy alone in locoregional disease. Studies in operable esophageal cancer comparing chemo-radiotherapy with surgery alone have not so far been reported.
在转移性食管癌中，单药或联合化疗仅能使少数患者获得短期缓解。因此，仅应对特定患者进行治疗。超过半数的局部区域疾病患者通过以顺铂为基础的联合化疗会有显著改善。然而，迄今为止，这尚未显示出对总生存期有影响。在局部区域疾病方面，联合放化疗优于单纯放疗。目前尚无关于可手术食管癌中比较放化疗与单纯手术的研究报道。
