Witte Tanja Semira, Schäfer-Somi Sabine
Centre for Artificial Insemination and Embryo Transfer, University of Veterinary Science, Vienna, Veterinärplatz 1, A-1210 Vienna, Austria.
Anim Reprod Sci. 2007 Dec;102(3-4):181-93. doi: 10.1016/j.anireprosci.2007.07.007. Epub 2007 Jul 31.
The aim of this paper was to review the effects of some important substances involved in the induction of sperm plasma membrane changes referred to as acrosome reaction, namely cholesterol (C), calcium (Ca(2+)) and progesterone (P(4)). For this purpose, mechanisms of capacitation and acrosome reaction (AR) as well as the processes, C, Ca(2+) and P(4) are involved in, are described. Subsequently, to get a better insight into possible beneficial and detrimental effects on sperm function, the occurrence of these molecules in semen extenders is discussed.
本文旨在综述一些参与诱导精子质膜变化（即顶体反应）的重要物质的作用，这些物质包括胆固醇（C）、钙（Ca(2+)）和孕酮（P(4)）。为此，本文描述了获能和顶体反应（AR）的机制以及C、Ca(2+)和P(4)所涉及的过程。随后，为了更好地了解这些分子对精子功能可能产生的有益和有害影响，本文讨论了它们在精液稀释剂中的存在情况。
