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老年急诊科患者的不适当用药情况。

Inappropriate prescribing in an older ED population.

作者信息

Hustey Fredric M, Wallis Nicole, Miller Jonathan

机构信息

Department of Emergency Medicine, Cleveland Clinic, Cleveland, OH 44195, USA.

出版信息

Am J Emerg Med. 2007 Sep;25(7):804-7. doi: 10.1016/j.ajem.2007.01.018.

Abstract

The objective of this study was to determine the prevalence of potentially inappropriate medication (PIMs) use in older emergency department (ED) patients based on the updated 2002 Beers criteria. This was a retrospective analysis of 352 consecutive ED visits by patients aged 65 years and older. The mean number of medications taken was 8.4 per patient. In the study population, 111 (32%; 95% confidence interval [CI], 27-36) of 352 patients were taking at least 1 PIM at ED presentation. Propoxyphene/acetaminophen (24/352, 7%; 95% CI, 4-10), muscle relaxants (14/352, 4%; 95% CI, 2-7), and antihistamines (12/352, 3%; 95% CI, 2-6) were the most common PIMs. Among 101 of 193 patients discharged home from the ED with a new prescription, 13 (13%; 95% CI, 6-19) were also given PIMs. The most common PIMs were propoxyphene/acetaminophen (3/101; 95% CI, 1-8), diazepam (3/101; 95% CI, 1-8), cyclobenzaprine (2/101, 2%; 95% CI, 0-7), and diphenhydramine (2/101, 2%; 95% CI, 0-7). Outpatient PIM use in older ED patients is highly prevalent. Further education is needed regarding prescribing practices in this population group.

摘要

本研究的目的是根据2002年更新的《Beers标准》确定老年急诊科患者中潜在不适当用药(PIMs)的使用情况。这是一项对352例65岁及以上患者连续急诊就诊情况的回顾性分析。每位患者服用药物的平均数量为8.4种。在研究人群中,352例患者中有111例(32%;95%置信区间[CI],27 - 36)在急诊就诊时至少服用1种PIM。丙氧芬/对乙酰氨基酚(24/352,7%;95% CI,4 - 10)、肌肉松弛剂(14/352,4%;95% CI,2 - 7)和抗组胺药(12/352,3%;95% CI,2 - 6)是最常见的PIMs。在193例从急诊出院并开具新处方的患者中,有101例,其中13例(13%;95% CI,6 - 19)也被开具了PIMs。最常见的PIMs是丙氧芬/对乙酰氨基酚(3/101;95% CI,1 - 8)、地西泮(3/101;95% CI,1 - 8)、环苯扎林(2/101,2%;95% CI,0 - 7)和苯海拉明(2/101,2%;95% CI,0 - 7)。老年急诊患者门诊使用PIMs的情况非常普遍。需要对该人群组的处方行为进行进一步教育。

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