Amunts K, Schleicher A, Zilles K
Institute of Neurosciences and Biophysics-Medicine (INB 3), Research Centre Juelich, 52428 Juelich, Germany.
Neuroimage. 2007 Oct 1;37(4):1061-5; discussion 1066-8. doi: 10.1016/j.neuroimage.2007.02.037. Epub 2007 Mar 3.
The present paper reviews that macroanatomical landmarks are problematic for a reliable and sufficiently precise localization of clusters of activation obtained by functional imaging because sulcal and gyral patterns are extremely variable and macroanatomical landmarks do not match (in nearly all cases) architectonically defined borders. It argues that cytoarchitectonic probabilistic maps currently offer the most precise tool for the localization of brain functions as obtained from functional imaging studies. Finally, it provides some examples that cytoarchitecture is more than localization with respect to a particular brain region because it reflects the inner organization of cortical areas and, furthermore, functional principles of the brain.
本文回顾了宏观解剖学标志对于通过功能成像获得的激活簇进行可靠且足够精确的定位存在问题，因为脑沟和脑回模式极具变异性，且宏观解剖学标志（几乎在所有情况下）与构筑学定义的边界不匹配。文章认为，细胞构筑概率图谱目前为从功能成像研究中获得的脑功能定位提供了最精确的工具。最后，文章给出了一些例子，说明细胞构筑不仅仅是相对于特定脑区的定位，因为它反映了皮质区域的内部组织，此外还反映了大脑的功能原理。
