Roland Malcolm Mounger Sawers, Baran Alp Sinan, Richert Allen Carl
The University of Mississippi Medical Center, Sleep Disorders Center, Department of Psychiatry, Jackson, MS 39216-4505, USA.
Sleep Med. 2008 May;9(4):451-3. doi: 10.1016/j.sleep.2007.07.012. Epub 2007 Sep 17.
Gastroesophageal reflux is a suspected cause of sleep-related laryngospasm [Thurnheer R, Henz A, Knoblauch A. Sleep-related laryngospasm. Eur Respir J 1997;10:2084-6], but the relationship has not been directly documented by polysomnography (PSG). We report the case of an eight-year-old girl with asthma who was referred for evaluation of awakenings with respiratory distress. The description of her events included stridorous breathing suggestive of laryngospasm. A PSG was performed with esophageal pH monitoring, and during the recording pH dropped below four on nine occasions. Following two of the pH drops, acute respiratory distress with stridor was documented in video and audio recording, supporting a causal relationship between sleep-related gastroesophageal reflux and laryngospasm.
胃食管反流被怀疑是与睡眠相关的喉痉挛的一个病因[图恩希尔R，亨茨A，克诺布劳赫A。与睡眠相关的喉痉挛。《欧洲呼吸杂志》1997年；10：2084 - 2086]，但这种关系尚未通过多导睡眠图（PSG）直接记录。我们报告一例8岁哮喘女童病例，该女童因呼吸窘迫惊醒前来评估。对其发作情况的描述包括提示喉痉挛的喘鸣呼吸。进行了一项带有食管pH监测的多导睡眠图检查，记录期间pH值有9次降至4以下。在其中两次pH值下降后，视频和音频记录显示出现伴有喘鸣的急性呼吸窘迫，支持了与睡眠相关的胃食管反流和喉痉挛之间的因果关系。
