[1-乙氧基氮杂环十三烷的抗溃疡作用可能机制分析]
[An analysis of the possible mechanism of the ulcerostatic action of 1-ethoxysilatrane].
作者信息
Rasulov M M, Kuznetsov I G, Bartkova L K, Suslova S K, Belousov A A, Voronkov M G
出版信息
Izv Akad Nauk SSSR Biol. 1991 Jul-Aug(4):522-7.
PMID:1787228
Abstract
Stimulating effect of 1-ethoxysilatrane on healing processes of experimental stomach ulcers was studied in rats. 1-ethoxysilatrane inhibited lipid peroxidation in blood and stomach wall tissues, interacted with artificial membranes, and affected the rate of mitochondrial respiration in liver. A hypothesis is put forward on the membranotropic effect of 1-ethoxysilatrane which underlies its ulcerostatic effect.
摘要
研究了1-乙氧基硅氮烷对大鼠实验性胃溃疡愈合过程的刺激作用。1-乙氧基硅氮烷抑制血液和胃壁组织中的脂质过氧化，与人工膜相互作用，并影响肝脏线粒体呼吸速率。提出了1-乙氧基硅氮烷的膜otropic作用假说，该作用是其抗溃疡作用的基础。
Zotero 插件