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退行性腰椎侧弯后路融合与内固定术的并发症

Complications in posterior fusion and instrumentation for degenerative lumbar scoliosis.

作者信息

Cho Kyu-Jung, Suk Se-Il, Park Seung-Rim, Kim Jin-Hyok, Kim Sung-Soo, Choi Won-Kee, Lee Kang-Yoon, Lee Seung-Ryol

机构信息

Inha University Hospital, Incheon, Korea.

出版信息

Spine (Phila Pa 1976). 2007 Sep 15;32(20):2232-7. doi: 10.1097/BRS.0b013e31814b2d3c.

Abstract

STUDY DESIGN

Radiographic analysis was performed retrospectively. Outcomes and complications were collected prospectively.

OBJECTIVES

To assess complications after posterior fusion and instrumentation for degenerative lumbar scoliosis, to determine risk factors of complications, and to analyze the clinical outcomes of surgery.

SUMMARY OF BACKGROUND DATA

The complications after degenerative lumbar scoliosis surgery have reported to be high. Risk factors for developing complications are unknown.

METHODS

Forty-seven patients (average age, 66.6 years; range, 48-83 years) with degenerative lumbar scoliosis undergoing posterior fusion and instrumentation were analyzed. Seven patients had additional posterior lumbar interbody fusion at the lumbosacral junction. The average number of levels fused was 4.7 +/- 2.2 segments. We evaluated the early perioperative (<3 months after surgery) and late complications.

RESULTS

There were 14 early perioperative complications and 18 late complications. There was 1 case of mortality by pulmonary embolism. Early complications included ileus, urinary tract infection, transient delirium, superficial infection, and neurologic deficit. Late complications included adjacent segment diseases, pseudarthrosis, and loosening of screws. Adjacent segment disease developed at the proximal segment in 10 patients and at the distal segment in 5 patients. Pseudarthrosis was noted at the lumbosacral junction in 2 patients. Revision surgery was performed in 7 patients. Older patients (>65 years) had the tendency to increase early complications without statistical difference (P = 0.053). Excessive intraoperative blood loss was the most significant risk factor for the development of early perioperative complications, and number of levels fused was related to blood loss. Operative time and multiple medical comorbidities were not associated with higher complication rate. There were no specific factors related to the development of late complications.

CONCLUSION

The complication rate after posterior fusion and instrumentation for degenerative lumbar scoliosis was 68%. Abundant blood loss was a significant risk factor for early perioperative complications. The improvement of Oswestry disability index was less in patients with late complications.

摘要

研究设计

进行回顾性影像学分析。前瞻性收集结果和并发症情况。

目的

评估退行性腰椎侧弯后路融合内固定术后的并发症,确定并发症的危险因素,并分析手术的临床结果。

背景资料总结

据报道,退行性腰椎侧弯手术后的并发症发生率较高。发生并发症的危险因素尚不清楚。

方法

分析47例行退行性腰椎侧弯后路融合内固定术的患者(平均年龄66.6岁;范围48 - 83岁)。7例患者在腰骶部行额外的后路腰椎椎间融合术。平均融合节段数为4.7±2.2个节段。我们评估了早期围手术期(术后<3个月)和晚期并发症。

结果

有14例早期围手术期并发症和18例晚期并发症。有1例因肺栓塞死亡。早期并发症包括肠梗阻、尿路感染、短暂性谵妄、浅表感染和神经功能缺损。晚期并发症包括相邻节段疾病、假关节形成和螺钉松动。相邻节段疾病在近端节段发生于10例患者,在远端节段发生于5例患者。2例患者在腰骶部出现假关节形成。7例患者进行了翻修手术。老年患者(>65岁)早期并发症有增加趋势,但无统计学差异(P = 0.053)。术中失血过多是早期围手术期并发症发生的最显著危险因素,融合节段数与失血量有关。手术时间和多种内科合并症与较高的并发症发生率无关。晚期并发症的发生无特定相关因素。

结论

退行性腰椎侧弯后路融合内固定术后的并发症发生率为68%。大量失血是早期围手术期并发症的重要危险因素。晚期并发症患者的奥斯威斯利功能障碍指数改善较少。

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