Schärer L
Dermatopathologische Gemeinschaftspraxis, Siemensstrasse 6/1, 88048, Friedrichshafen.
Pathologe. 2007 Nov;28(6):430-6. doi: 10.1007/s00292-007-0941-7.
Melanocytic nevi at special anatomical sites can evoke a histological picture easily leading to the false diagnosis of a highly atypical, dysplastic nevus or even malignant melanoma. It is therefore most important to recognize these lesions in order to differentiate them from "true" dysplastic nevi or malignant melanomas. The anatomical regions recognized as "special sites" are the head and neck, especially the ear, the milk line (axilla, mamae, mamillae, umbilicus, groin), acral regions (palms and soles, knee, dorsum of the foot) and flexural sites. The specific histological picture of these nevi is described as well as differential diagnostic considerations to differentiate these lesions from malignant melanomas.
特殊解剖部位的黑素细胞痣可呈现出一种组织学表现,容易导致对高度不典型、发育异常痣甚至恶性黑色素瘤的误诊。因此,识别这些病变以便将它们与“真正的”发育异常痣或恶性黑色素瘤区分开来至关重要。被视为“特殊部位”的解剖区域包括头颈部,尤其是耳部、乳线(腋窝、乳房、乳头、脐部、腹股沟)、肢端部位(手掌、足底、膝部、足背)以及屈侧部位。本文描述了这些痣的特定组织学表现以及将这些病变与恶性黑色素瘤区分开来的鉴别诊断要点。