Mulhall Kevin J, Saleh Khaled J, Thompson Corey A, Severson Erik P, Palmer David H
Department of Orthopaedic Surgery, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland.
Arch Orthop Trauma Surg. 2008 Mar;128(3):249-54. doi: 10.1007/s00402-007-0450-4. Epub 2007 Sep 15.
We evaluated the long-term outcomes for combined, bilateral total knee and hip arthroplasty performed on a group of very young patients with juvenile rheumatoid arthritis.
Six consecutive patients with a mean age of 14 years at the time of hip replacement and 16 years at knee replacement were analyzed. Five of the six patients were wheelchair dependent pre-operatively. All knee components had uncemented fixation, while the hip replacements were a mixed group of cemented and uncemented prostheses.
Clinical and radiographic follow-up at a mean duration of 13.8 years for the hips and 17.3 years for the knees demonstrated four of the six patients were unlimited community ambulators, one a limited community ambulator and the remaining patient a household ambulator. Failure, defined as revision of any of the components or definite radiographic loosening, occurred in three knees (two patients) and five hips (three patients).
These good long-term functional results in a relatively very young population indicate that an early and aggressive approach to multiple joint disease is an appropriate option at a young age for patients with juvenile rheumatoid arthritis with severe disability and pain refractory to conservative management.
我们评估了一组幼年类风湿关节炎的非常年轻患者接受联合双侧全膝关节和全髋关节置换术的长期疗效。
分析了6例患者,髋关节置换时平均年龄为14岁,膝关节置换时平均年龄为16岁。6例患者中有5例术前依赖轮椅。所有膝关节假体均采用非骨水泥固定,而髋关节置换假体则是骨水泥型和非骨水泥型的混合组。
髋关节平均随访13.8年,膝关节平均随访17.3年,临床和影像学随访显示6例患者中有4例能在社区无限制行走,1例能在社区有限行走,其余1例只能在家中行走。定义为任何部件翻修或明确的影像学松动的失败情况发生在3个膝关节(2例患者)和5个髋关节(3例患者)。
在相对非常年轻的人群中取得的这些良好长期功能结果表明,对于患有严重残疾且保守治疗难以缓解疼痛的幼年类风湿关节炎患者,早期积极治疗多关节疾病在年轻时是一种合适的选择。