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酗酒者对酒精去抑制作用的敏感性增加。

Increased sensitivity to the disinhibiting effects of alcohol in binge drinkers.

作者信息

Marczinski Cecile A, Combs Stewart W, Fillmore Mark T

机构信息

Department of Psychology, University of Kentucky, Lexington, KY 40506-0044, USA.

出版信息

Psychol Addict Behav. 2007 Sep;21(3):346-54. doi: 10.1037/0893-164X.21.3.346.


DOI:10.1037/0893-164X.21.3.346
PMID:17874885
Abstract

Heavy episodic alcohol use, or binge drinking, is a serious public health problem. Binge drinking is endemic in college students and has resulted in numerous alcohol-related tragedies, including acute alcohol poisonings, falls, and automobile collisions. Such negative outcomes might occur because binge drinkers are generally more impulsive, and this impulsivity might be exacerbated under alcohol. The purpose of this study was to examine this hypothesis by comparing the acute effects of alcohol on a cognitive measure of behavioral control in binge and nonbinge drinkers. The results indicated that binge drinkers act more impulsively and report feeling more stimulated under an acute 0.65 g/kg dose of alcohol compared to nonbinge drinkers. The present finding of a heightened disinhibitory reaction to alcohol in binge drinkers may help explain the link between impulsivity and problem drinking at a more fundamental level of behavioral control.

摘要

大量偶发性饮酒,即暴饮,是一个严重的公共卫生问题。暴饮在大学生中很普遍,并导致了许多与酒精相关的悲剧,包括急性酒精中毒、摔倒和汽车碰撞。出现这些负面后果可能是因为暴饮者通常更冲动,而这种冲动在饮酒时可能会加剧。本研究的目的是通过比较酒精对暴饮者和非暴饮者行为控制的认知测量的急性影响来检验这一假设。结果表明,与非暴饮者相比,暴饮者在急性摄入0.65克/千克酒精剂量下行为更冲动,且报告感觉更兴奋。目前关于暴饮者对酒精的去抑制反应增强的发现,可能有助于在行为控制的更基本层面上解释冲动与问题饮酒之间的联系。

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Drug Alcohol Depend. 2023-7-1

[2]
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Alcohol Clin Exp Res (Hoboken). 2023-2

[3]
Ghrelin Predicts Stimulant and Sedative Effects of Alcohol in Heavy Drinkers.

Alcohol Alcohol. 2023-1-9

[4]
Heightened sensitivity to the disinhibiting effect of alcohol in women during the late follicular phase of the menstrual cycle.

Exp Clin Psychopharmacol. 2023-8

[5]
Acute rewarding and disinhibiting effects of alcohol as indicators of drinking habits.

Psychopharmacology (Berl). 2021-1

[6]
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BMC Psychol. 2020-1-7

[7]
Poor inhibitory control is associated with greater stimulation and less sedation following alcohol.

Psychopharmacology (Berl). 2019-12-12

[8]
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Psychol Addict Behav. 2019-10-10

[9]
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J Stud Alcohol Drugs. 2019-1

[10]
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