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Serious haematological toxicity of cyclophosphamide in relation to CYP2B6, GSTA1 and GSTP1 polymorphisms.

作者信息

Tran Agnès, Bournerias François, Le Beller Christine, Mir Olivier, Rey Elisabeth, Pons Gérard, Delahousse Michel, Tréluyer Jean-Marc

出版信息

Br J Clin Pharmacol. 2008 Feb;65(2):279-80. doi: 10.1111/j.1365-2125.2007.03020.x. Epub 2007 Sep 13.

DOI:10.1111/j.1365-2125.2007.03020.x
PMID:17875191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2291223/
Abstract
摘要

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Serious haematological toxicity of cyclophosphamide in relation to CYP2B6, GSTA1 and GSTP1 polymorphisms.环磷酰胺与CYP2B6、GSTA1和GSTP1基因多态性相关的严重血液学毒性。
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本文引用的文献

1
Clinical pharmacokinetics of cyclophosphamide.环磷酰胺的临床药代动力学
Clin Pharmacokinet. 2005;44(11):1135-64. doi: 10.2165/00003088-200544110-00003.
2
Pharmacogenetics of cyclophosphamide in patients with hematological malignancies.血液系统恶性肿瘤患者中环磷酰胺的药物遗传学
Eur J Pharm Sci. 2006 Jan;27(1):54-61. doi: 10.1016/j.ejps.2005.08.008. Epub 2005 Sep 23.
3
Association of cyclophosphamide pharmacokinetics to polymorphic cytochrome P450 2C19.环磷酰胺药代动力学与细胞色素P450 2C19基因多态性的关联
Pharmacogenomics J. 2005;5(6):365-73. doi: 10.1038/sj.tpj.6500330.
4
Reversal of multiple drug resistance in cholangiocarcinoma by the glutathione S-transferase-pi-specific inhibitor O1-hexadecyl-gamma-glutamyl-S-benzylcysteinyl-D-phenylglycine ethylester.谷胱甘肽S-转移酶π特异性抑制剂O1-十六烷基-γ-谷氨酰-S-苄基半胱氨酰-D-苯甘氨酸乙酯逆转胆管癌中的多药耐药性
J Pharmacol Exp Ther. 2003 Sep;306(3):861-9. doi: 10.1124/jpet.103.052696. Epub 2003 Jun 12.
5
Association between a glutathione S-transferase A1 promoter polymorphism and survival after breast cancer treatment.谷胱甘肽S-转移酶A1启动子多态性与乳腺癌治疗后生存率之间的关联。
Int J Cancer. 2003 Mar 1;103(6):810-4. doi: 10.1002/ijc.10896.
6
Allelic variants of the human glutathione S-transferase P1 gene confer differential cytoprotection against anticancer agents in Escherichia coli.人类谷胱甘肽S-转移酶P1基因的等位基因变体对大肠杆菌中的抗癌药物具有不同的细胞保护作用。
Pharmacogenetics. 2002 Oct;12(7):543-53. doi: 10.1097/00008571-200210000-00006.