de Wit P J G M
Wageningen University, Laboratory of Phytopathology and Wageningen Centre for Biosystems Genomics, Binnenhaven 5, Wageningen, The Netherlands.
Cell Mol Life Sci. 2007 Nov;64(21):2726-32. doi: 10.1007/s00018-007-7284-7.
Plants have an innate immunity system to defend themselves against pathogens. With the primary immune system, plants recognize microbe-associated molecular patterns (MAMPs) of potential pathogens through pattern recognition receptors (PRRs) that mediate a basal defense response. Plant pathogens suppress this basal defense response by means of effectors that enable them to cause disease. With the secondary immune system, plants have gained the ability to recognize effector-induced perturbations of host targets through resistance proteins (RPs) that mediate a strong local defense response that stops pathogen growth. Both primary and secondary immune responses in plants depend on germ line-encoded PRRs and RPs. During induction of local immune responses, systemic immune responses also become activated, which predispose plants to become more resistant to subsequent pathogen attacks. This review gives an update on recent findings that have enhanced our understanding of plant innate immunity and the arms race between plants and their pathogens.
植物拥有一种先天性免疫系统来抵御病原体。借助初级免疫系统,植物通过模式识别受体(PRR)识别潜在病原体的微生物相关分子模式(MAMP),这些受体介导基础防御反应。植物病原体通过效应子抑制这种基础防御反应,这些效应子使它们能够引发疾病。借助次级免疫系统,植物获得了通过抗性蛋白(RP)识别效应子诱导的宿主靶标扰动的能力,这些抗性蛋白介导强烈的局部防御反应,从而阻止病原体生长。植物的初级和次级免疫反应都依赖于种系编码的PRR和RP。在局部免疫反应诱导期间,系统免疫反应也会被激活,这使植物更易于对后续病原体攻击产生更强的抗性。本综述介绍了最近的研究发现,这些发现增进了我们对植物先天性免疫以及植物与其病原体之间军备竞赛的理解。