Takaishi Kazumi, Nakajo Nobuyoshi
Department of Dental Anesthesiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8504.
Masui. 2007 Sep;56(9):1078-80.
A 22-year-old man with mental disabilities with the history of neuroleptic malignant syndrome and heat stroke was scheduled for dental treatment under general anesthesia. Heat stroke and neuroleptic malignant syndrome are related to malignant hyperthermia. We suggested the patient and family to undergo preoperative screening tests for malignant hyperthermia susceptibility, but they rejected. We selected slow induction using nitrous oxide, oxygen and sevoflurane to prevent excitement and anxiety for placing a catheter in a peripheral vein. We were very cautious in primary symptoms of malignant hyperthermia, i.e., tachycardia, increased end-tidal carbon dioxide, and rigidity of masseter. In the perioperative period, no complications occurred.
一名22岁患有精神残疾且有抗精神病药恶性综合征和中暑病史的男子计划在全身麻醉下接受牙科治疗。中暑和抗精神病药恶性综合征与恶性高热有关。我们建议患者及其家属接受恶性高热易感性的术前筛查,但他们拒绝了。我们选择使用氧化亚氮、氧气和七氟醚进行缓慢诱导,以防止在置入外周静脉导管时出现兴奋和焦虑。我们对恶性高热的主要症状,即心动过速、呼气末二氧化碳增加和咬肌僵硬非常谨慎。围手术期未发生并发症。