Bielńska-Warezak Dominika, Nowicki Roman
Klinika Dermatologii, Wenerologii i Alergologii AM w Gdańsku.
Pol Merkur Lekarski. 2005 Feb;18(104):241-4.
Atopic dermatitis (AD) is one of the most common chronic, recurrent, inflammatory skin disease. Its pathogenesis is still not fully understood. The lipophilic yeasts Malassezia sp, members of the normal human cutaneous flora, can be the factors that may contribute to AD. Specific IgE antibodies to Malassezia sp., skin prick tests, atopy patch tests indicate that these yeasts may be an important allergen especially in patients with AD localized on the head and neck. During exacerbations of the AD, supplementary treatment with proper antifungal agents has been shown to be of great value.
特应性皮炎（AD）是最常见的慢性、复发性炎症性皮肤病之一。其发病机制仍未完全明确。亲脂性酵母马拉色菌属是人类正常皮肤菌群的成员，可能是导致特应性皮炎的因素。针对马拉色菌属的特异性IgE抗体、皮肤点刺试验、特应性斑贴试验表明，这些酵母可能是一种重要的变应原，尤其是在头颈部患有特应性皮炎的患者中。在特应性皮炎病情加重期间，使用适当的抗真菌药物进行辅助治疗已显示出具有重要价值。
