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调整房室模型以解释瘤胃中挥发性脂肪酸代谢的同位素稀释数据，使其适用于非稳态和单剂量注射情况。

Adaptation of compartmental schemes for interpreting isotope dilution data on volatile fatty acid metabolism in the rumen to the non-steady state and for single-dose injection.

作者信息

France J, Siddons R C, Dhanoa M S

机构信息

AFRC Institute of Grassland and Environmental Research, Hurley, Maidenhead, Berkshire, U.K.

出版信息

J Theor Biol. 1991 Nov 21;153(2):247-54. doi: 10.1016/s0022-5193(05)80425-4.

DOI:10.1016/s0022-5193(05)80425-4
PMID:1787739
Abstract

A unifying mathematical analysis of the one-pool and three-pool schemes for estimating acetate, propionate and butyrate production in the rumen from isotope dilution data is presented. Emphasis is given to non-steady-state conditions and to the administration of isotope as a single injection. The single-pool representation is also derived as a special case of the three-pool representation by assuming that the external fluxes are directly proportional to their concentrations in the rumen.

摘要

本文提出了一种统一的数学分析方法，用于根据同位素稀释数据估算瘤胃中乙酸、丙酸和丁酸的产生量，该方法涉及单池和三池模型。重点讨论了非稳态条件以及作为单次注射的同位素给药方式。单池模型也可作为三池模型的一种特殊情况推导得出，即假设外部通量与其在瘤胃中的浓度成正比。

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