Armentano L E, Young J W
J Nutr. 1983 Jun;113(6):1265-77. doi: 10.1093/jn/113.6.1265.
A study was conducted to determine effects of monensin supplementation on production and interconversion rates of rumen acetate, propionate, and butyrate and plasma acetate. Measurements were made by isotope dilution techniques in four Holstein steers fed a 70% alfalfa hay, 30% corn ration. In addition, a general kinetic method for solution of open systems has been applied to quantify metabolism of the rumen volatile fatty acids and glucose and the production of CO2. Dietary monensin increased rumen propionate production at the expense of rumen acetate production so that total volatile fatty acid production was unchanged. Butyrate production tended to increase, indicating that decreased acetate production may result in diversion of hexose to propionate and butyrate production and direction of reducing equivalents away from methane production. These changes were calculated to increase rumen fermentation efficiency by 6%. Oxidation of the rumen volatile fatty acids and systemic plasma glucose accounted for only 35% of CO2 production.
进行了一项研究，以确定添加莫能菌素对瘤胃乙酸、丙酸、丁酸以及血浆乙酸的生成和相互转化率的影响。通过同位素稀释技术对四头荷斯坦公牛进行测量，这些公牛饲喂含70%苜蓿干草和30%玉米的日粮。此外，一种用于开放系统求解的通用动力学方法已被应用于量化瘤胃挥发性脂肪酸和葡萄糖的代谢以及二氧化碳的生成。日粮莫能菌素增加了瘤胃丙酸的生成，同时降低了瘤胃乙酸的生成，因此总挥发性脂肪酸的生成量未变。丁酸生成量有增加的趋势，这表明乙酸生成量的减少可能导致己糖转向丙酸和丁酸的生成，并使还原当量的方向远离甲烷的生成。据计算，这些变化使瘤胃发酵效率提高了6%。瘤胃挥发性脂肪酸和全身血浆葡萄糖的氧化仅占二氧化碳生成量的35%。
