Fiszer U, Piotrowska K, Korlak J, Członkowska A
Institute of Psychiatry and Neurology, Warsaw, Poland.
Med Lab Sci. 1991 Jul;48(3):196-200.
It has been suggested that patients with idiopathic Parkinson's disease have altered functions of the immune system. We determined certain immunological parameters in groups of Parkinson's disease patients who have been i) treated and ii) not been treated, with levodopa. Changes in the immune functions were observed to be more profound in Parkinson's disease patients than in age-matched controls. Treatment with levodopa induced an increase in interleukin-1 synthesis, and in IgM and IgA levels in plasma, which suggest a possible selective action on cells of the immune system.
有人提出，特发性帕金森病患者的免疫系统功能发生了改变。我们测定了帕金森病患者组的某些免疫参数，这些患者分为两类：i）接受左旋多巴治疗的患者和ii）未接受左旋多巴治疗的患者。观察到帕金森病患者的免疫功能变化比年龄匹配的对照组更为显著。左旋多巴治疗导致白细胞介素-1合成增加，血浆中IgM和IgA水平升高，这表明对免疫系统细胞可能有选择性作用。
