Yamada Takumi, Kay G Neal
Division of Cardiovascular Diseases, Cardiac Rhythm Management Laboratory, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Curr Cardiol Rep. 2007 Sep;9(5):366-70. doi: 10.1007/BF02938363.
Catheter ablation of atrial fibrillation (AF) has made considerable advances over the past decade. Although pulmonary vein (PV) isolation has proven to be a reliable curative treatment, especially for paroxysmal AF, it still has several issues to resolve. Because the AF mechanisms are complex and multifactorial, especially in persistent or permanent AF, they cannot be eliminated altogether by PV isolation alone. Beyond PV isolation, several other techniques have shown promise in improving the long-term success. Several recent reports comparing the superiority between AF ablation and antiarrhythmic drug therapy have shown early evidence suggesting that AF ablation warrants consideration as a first-line therapy in selected patients.
在过去十年中，心房颤动（AF）的导管消融取得了长足进展。尽管肺静脉（PV）隔离已被证明是一种可靠的根治性治疗方法，尤其是对阵发性AF而言，但仍有几个问题有待解决。由于AF的机制复杂且多因素，特别是在持续性或永久性AF中，仅通过PV隔离无法完全消除这些机制。除了PV隔离之外，其他几种技术在提高长期成功率方面也显示出前景。最近几篇比较AF消融与抗心律失常药物治疗优越性的报告已显示出早期证据，表明在特定患者中，AF消融值得作为一线治疗方法加以考虑。
