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一项关于用于检测乳腺癌患者化疗引起的认知障碍的各种神经心理学测试敏感性的荟萃分析。

A meta-analysis of the sensitivity of various neuropsychological tests used to detect chemotherapy-induced cognitive impairment in patients with breast cancer.

作者信息

Jansen Catherine E, Miaskowski Christine A, Dodd Marilyn J, Dowling Glenna A

机构信息

Department of Physiological Nursing, The University of California, San Francisco, USA.

出版信息

Oncol Nurs Forum. 2007 Sep;34(5):997-1005. doi: 10.1188/07.ONF.997-1005.

DOI:10.1188/07.ONF.997-1005
PMID:17878128
Abstract

PURPOSE/OBJECTIVES: To identify which neuropsychological tests have been used to evaluate chemotherapy-induced impairment in various domains of cognitive function in patients with breast cancer and to determine the sensitivity of each of the tests through estimation of effect size.

DATA SOURCES

Original studies published from 1966-June 2006.

DATA SYNTHESIS

Although an array of neuropsychological tests are available to measure the various domains of cognitive function, information is lacking regarding the sensitivity and specificity of the tests to detect changes in cognitive function from chemotherapy.

CONCLUSIONS

This meta-analysis provides initial data on the sensitivity of some neuropsychological tests to determine chemotherapy-induced changes in cognitive function in patients with breast cancer.

IMPLICATIONS FOR NURSING

The identification of sensitive neuro-psychological tests is crucial to further understanding of chemotherapy-induced cognitive impairments.

摘要

目的/目标:确定哪些神经心理学测试被用于评估乳腺癌患者化疗引起的认知功能各领域损害,并通过效应大小估计来确定每项测试的敏感性。

数据来源

1966年至2006年6月发表的原始研究。

数据综合

尽管有一系列神经心理学测试可用于测量认知功能的各个领域,但缺乏关于这些测试检测化疗引起的认知功能变化的敏感性和特异性的信息。

结论

这项荟萃分析提供了一些神经心理学测试的敏感性的初步数据,以确定化疗引起的乳腺癌患者认知功能变化。

对护理的启示

识别敏感的神经心理学测试对于进一步了解化疗引起的认知障碍至关重要。

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