Taghavi Noushin, Nasrollahzadeh Dariush, Merat Shahin, Yazdanbod Abbas, Hormazdi Mahshid, Sotoudeh Masoud, Semnani Shahriar, Eslami Farhad, Marjani Haji-Amin, Fahimi Saman, Khademi Hooman, Malekzadeh Reza
Digestive Disease Research Center, Shariati Hospital, N Kargar St, Tehran 14144, Iran.
World J Gastroenterol. 2007 Oct 28;13(40):5367-70. doi: 10.3748/wjg.v13.i40.5367.
To define the sub site distribution of upper gastrointestinal cancers in three provinces of Iran.
The study was carried out in three provinces in Iran: Ardabil, Golestan, and Tehran. In Arbabil and Golestan, the data was collected from the sole referral center for gastrointestinal cancers and the local cancer registry. For Tehran province, data from two major private hospitals were used. All gastric and esophageal cancer patients diagnosed during the period from September 2000 and April 2002 were included in the study.
A total of 761 patients with upper gastrointestinal cancers were identified, 314 from Ardabil, 261 from Golestan, and 186 from Tehran. In Tehran, the relative rate of cancer increased from the upper esophagus to the distal stomach. In Golestan, the reverse pattern was observed. In Ardabil, the mid portion (distal esophagus and proximal stomach) was involved most frequently.
There were considerable variations in the sub site of upper gastrointestinal cancers in the three provinces studied. We cannot provide any explanation for this variation. Further research aimed at explaining the discrepancies in sub site distribution of upper gastrointestinal cancers may help identify important risk factors.
确定伊朗三个省份上消化道癌症的亚部位分布情况。
该研究在伊朗的三个省份开展：阿尔达比勒省、戈勒斯坦省和德黑兰省。在阿尔达比勒省和戈勒斯坦省，数据收集自胃肠癌唯一的转诊中心及当地癌症登记处。对于德黑兰省，使用了两家大型私立医院的数据。2000年9月至2002年4月期间诊断出的所有胃癌和食管癌患者均纳入本研究。
共确定了761例上消化道癌症患者，其中314例来自阿尔达比勒省，261例来自戈勒斯坦省，186例来自德黑兰省。在德黑兰，癌症相对发病率从上段食管到胃远端呈上升趋势。在戈勒斯坦省，观察到相反的模式。在阿尔达比勒省，中段（食管远端和胃近端）受累最为频繁。
在所研究的三个省份中，上消化道癌症的亚部位存在相当大的差异。我们无法对此差异作出任何解释。旨在解释上消化道癌症亚部位分布差异的进一步研究可能有助于识别重要的风险因素。
