Wilson Jason P, Massoll Nicole, Marshall Julia, Foss Robin M, Copeland Edward M, Grobmyer Stephen R
Department of Surgery, Division of Surgical Oncology, University of Florida, Gainesville, Florida, USA.
Am Surg. 2007 Aug;73(8):798-802.
Idiopathic granulomatous mastitis, also known as idiopathic granulomatous lobular mastitis, is a benign breast lesion that represents both a diagnostic and therapeutic dilemma. We report two cases of granulomatous mastitis recently evaluated and managed at our institution. To better understand this rare disease, we analyzed treatment outcomes in reported cases of granulomatous mastitis. One hundred sixteen cases were subsequently analyzed. Primary management strategies included observation (n = 9), steroids (n = 29), partial mastectomy (n = 75), and mastectomy (n = 3). Success rates with each treatment were observation, 56 per cent; steroids, 42 per cent; partial mastectomy, 79 per cent; and mastectomy, 100 per cent. Based on this analysis, we propose a clinically useful algorithm for both workup and management of these challenging cases.
特发性肉芽肿性乳腺炎，也称为特发性肉芽肿性小叶性乳腺炎，是一种良性乳腺病变，在诊断和治疗上都存在难题。我们报告了两例近期在我院评估和治疗的肉芽肿性乳腺炎病例。为了更好地了解这种罕见疾病，我们分析了已报道的肉芽肿性乳腺炎病例的治疗结果。随后分析了116例病例。主要治疗策略包括观察（9例）、使用类固醇（29例）、乳房部分切除术（75例）和乳房切除术（3例）。每种治疗方法的成功率分别为：观察，56%；类固醇，42%；乳房部分切除术，79%；乳房切除术，100%。基于此分析，我们提出了一种对这些具有挑战性病例的检查和治疗都具有临床实用性的算法。
