Hovanessian Larsen Linda J, Peyvandi Banafsheh, Klipfel Nancy, Grant Edward, Iyengar Geeta
Department of Radiology, University of Southern California Keck School of Medicine, USC/Norris Comprehensive Cancer Center, 1441 Eastlake Ave., Ste. 2315, Los Angeles, CA 90033, USA.
AJR Am J Roentgenol. 2009 Aug;193(2):574-81. doi: 10.2214/AJR.08.1528.
Granulomatous lobular mastitis is a rare chronic inflammatory disease that has clinical and radiologic findings similar to those of breast cancer. We performed a retrospective analysis of clinical, imaging, and treatment findings in 54 women diagnosed with granulomatous lobular mastitis between January 2000 and April 2008.
The imaging findings of granulomatous lobular mastitis overlap with those of malignancy. The most common presentation is a focal asymmetric density on mammography and an irregular hypoechoic mass with tubular extensions on ultrasound. Core biopsy is typically diagnostic. Once the diagnosis is established by tissue sampling, corticosteroids are the first line of treatment.
肉芽肿性小叶性乳腺炎是一种罕见的慢性炎症性疾病，其临床和影像学表现与乳腺癌相似。我们对2000年1月至2008年4月期间诊断为肉芽肿性小叶性乳腺炎的54例女性患者的临床、影像学和治疗结果进行了回顾性分析。
肉芽肿性小叶性乳腺炎的影像学表现与恶性肿瘤的表现重叠。最常见的表现是乳腺钼靶上的局灶性不对称密度影，以及超声检查时伴有管状延伸的不规则低回声肿块。粗针活检通常具有诊断价值。一旦通过组织取样确诊，皮质类固醇是一线治疗药物。
