Phellinone, a new furanone derivative from the Phellinus linteus KT&G PL-2.

Phellinone, a new furanone derivative, has been isolated from the stem-cooked rice culture broth of Phellinus linteus KT&GPL-2. Phellinone was purified by consecutive solvent partition, silica gel, preparative TLC and preparative HPLC. The structure of phellinone was assigned as a furanone derivative on the basis of various spectroscopic analyses, including Mass and NMR spectroscopies. Its molecular weight and formula were found to be 248 and C15H20O3, respectively, and showed antimicrobial activity against Bacillus subtilis IAM 1090.