Simon V
Institut für Medizinische Mikrobiologie, Universitätsmedizin Göttingen.
Laryngorhinootologie. 2007 Oct;86(10):738-45; quiz 746-7. doi: 10.1055/s-2007-966878.
Antibiotic resistance in bacteria, particularly MRSA (methicillin-resistant Staphylococcus (S.) aureus) is a crucial problem in the field of human medicine. Due to limited therapeutic choices, infections with these bacteria are causing higher morbidity and mortality compared to infections caused by MSSA (methicillin-susceptible S. AUREUS). In addition, these infections are also contributing to the economic burden of the public health system. Therefore, the rising proportion of MRSA can be seen as an enormous challenge in medical practice. In otorhinolaryngology, MRSA can cause different kinds of infections likewise, soft tissue infections, postoperative infections, otitis media, otitis externa, sinusitis and mastoiditis. To deal with this challenge, it is important to perform proper diagnostic and to provide appropriate antibiotic treatment which will ultimately help to lower selective pressure on bacterial population.
细菌的抗生素耐药性，尤其是耐甲氧西林金黄色葡萄球菌（MRSA），是人类医学领域的一个关键问题。由于治疗选择有限，与甲氧西林敏感金黄色葡萄球菌（MSSA）引起的感染相比，这些细菌引起的感染导致更高的发病率和死亡率。此外，这些感染也加重了公共卫生系统的经济负担。因此，MRSA比例的上升可被视为医疗实践中的巨大挑战。在耳鼻喉科，MRSA同样可引起不同类型的感染，如软组织感染、术后感染、中耳炎、外耳道炎、鼻窦炎和乳突炎。为应对这一挑战，进行正确的诊断并提供适当的抗生素治疗非常重要，这最终将有助于降低细菌群体的选择压力。
