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在快速涟漪期间,神经元会暂停一下。

Neurons skip a beat during fast ripples.

作者信息

Staley Kevin J

机构信息

Neurology Department, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.

出版信息

Neuron. 2007 Sep 20;55(6):828-30. doi: 10.1016/j.neuron.2007.09.005.

DOI:10.1016/j.neuron.2007.09.005
PMID:17880888
Abstract

Fast ripples are EEG transients emanating from epileptic foci, but fast-ripple frequencies far exceed maximal neuronal firing rates. In this issue of Neuron, Menendez de la Prida and coworkers propose that out-of-phase firing of a subpopulation of neurons during physiological ripple activity effectively doubles the ripple frequency to produce fast ripples.

摘要

快速涟漪是源自癫痫病灶的脑电图瞬变信号,但快速涟漪频率远远超过神经元的最大放电频率。在本期《神经元》杂志中,梅嫩德斯·德拉·普里达及其同事提出,在生理性涟漪活动期间,神经元亚群的不同步放电有效地使涟漪频率翻倍,从而产生快速涟漪。

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