Staley Kevin J
Neurology Department, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
Neuron. 2007 Sep 20;55(6):828-30. doi: 10.1016/j.neuron.2007.09.005.
Fast ripples are EEG transients emanating from epileptic foci, but fast-ripple frequencies far exceed maximal neuronal firing rates. In this issue of Neuron, Menendez de la Prida and coworkers propose that out-of-phase firing of a subpopulation of neurons during physiological ripple activity effectively doubles the ripple frequency to produce fast ripples.
快速涟漪是源自癫痫病灶的脑电图瞬变信号,但快速涟漪频率远远超过神经元的最大放电频率。在本期《神经元》杂志中,梅嫩德斯·德拉·普里达及其同事提出,在生理性涟漪活动期间,神经元亚群的不同步放电有效地使涟漪频率翻倍,从而产生快速涟漪。