Mathew Mary, Joseph Benjamin
Department of Pathology, Kasturba Medical College, Manipal, Karnataka.
Indian J Pathol Microbiol. 2007 Jul;50(3):565-7.
Adamantinoma of the long bones are uncommon, slow growing tumors with a predilection for the tibia. A special rare variant known as the osteofibrous dysplasia-like adamantinoma or differentiated adamantinoma is thought to be a precursor of the classic adamantinoma. We report a case in a 24 year old female who presented with pain and lytic lesion of the left tibia. Microscopy showed a tumor composed predominantly of osteofibrous dysplasia-like areas with focal cytokeratin positive epithelial islands. This case is highlighted because of its rarity, its association with good prognosis and possible misdiagnosis as osteofibrous dysplasia.
长骨造釉细胞瘤是一种罕见的、生长缓慢的肿瘤,好发于胫骨。一种特殊的罕见变异型,称为骨纤维结构不良样造釉细胞瘤或分化型造釉细胞瘤,被认为是经典造釉细胞瘤的前驱病变。我们报告一例24岁女性患者,她因左胫骨疼痛和溶骨性病变就诊。显微镜检查显示肿瘤主要由骨纤维结构不良样区域组成,并伴有局灶性细胞角蛋白阳性上皮岛。该病例因其罕见性、与良好预后的相关性以及可能被误诊为骨纤维结构不良而受到关注。