De Padua Michelle, Gupta Noopur, Broor S L, Govil Deepak
Department of Pathology, Indraprastha Apollo Hospitals, New Delhi.
Indian J Pathol Microbiol. 2007 Jul;50(3):568-9.
The authors present a case of duodenal angiomyolipoma. Angiomyolipoma is a benign neoplasm, the most common site being the kidney. Extrarenal angiomyolipomas are rare. Only one case of duodenal angiomyolipoma has been reported. A 66 year old man presented with GI bleeding for two years. Endoscopy revealed a duodenal polyp which on histopathology revealed features of angiomyolipoma. On immunohistochemistry, smooth muscle component was positive for Smooth Muscle Actin. HMB-45 showed mild focal positivity. Patient had no history of tuberous sclerosis. Surgical excision of angiomyolipoma is usually curative with rare cases of local recurrence.
作者报告了一例十二指肠血管平滑肌脂肪瘤。血管平滑肌脂肪瘤是一种良性肿瘤，最常见的部位是肾脏。肾外血管平滑肌脂肪瘤很罕见。仅报道过一例十二指肠血管平滑肌脂肪瘤。一名66岁男性因胃肠道出血两年就诊。内镜检查发现一个十二指肠息肉，组织病理学检查显示为血管平滑肌脂肪瘤特征。免疫组化显示，平滑肌成分平滑肌肌动蛋白呈阳性。HMB-45显示轻度局灶性阳性。患者无结节性硬化症病史。血管平滑肌脂肪瘤手术切除通常可治愈，局部复发罕见。
