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从一例真菌性鼻-鼻窦炎病例中分离出构巢曲霉:病例报告

Isolation of Aspergillus nidulans from a case of fungal rhinosinusitis: a case report.

作者信息

Shah Parul D, Deokule Jyoti S

机构信息

Department of Microbiology, Smt. N.H.L. Municipal Medical College, Sheth Vadilal Sarabhai General Hospital, Ellisbridge, Ahmedabad.

出版信息

Indian J Pathol Microbiol. 2007 Jul;50(3):677-8.

Abstract

A rare species i.e. A. nidulans is reported as a causative agent of allergic fungal rhinosinusitis in this study. It is an increasingly recognized type of chronic recurring hypertrophic sinus disease. There are more than 185 species of aspergillus and over 95% of all infections are caused by A. fumigatus, A. flavus and A. niger. A. fumigatus alone accounts for the large majority of cases of both invasive and non invasive aspergillosis. A young immunocompetent lady presented with bilateral nasal obstruction due to multiple polypoid mass at Sheth Vadilal Sarabhai General Hospital, Ahmedabad. Provisional diagnosis of sinonasal polyposis possibly due to fungal cause with infiltration in to nasal cavity was made. Bilateral functional endoscopic sinus surgery with polypectomy was done. The specimen was examined by standard methods and the fungus was identified as A. nidulans by slide culture.

摘要

在本研究中,一种罕见物种即构巢曲霉被报告为变应性真菌性鼻鼻窦炎的致病因子。它是一种越来越被认可的慢性复发性肥厚性鼻窦疾病类型。曲霉属有超过185个物种,所有感染中超过95%是由烟曲霉、黄曲霉和黑曲霉引起的。仅烟曲霉就占侵袭性和非侵袭性曲霉病大多数病例。一名年轻的免疫功能正常女性在艾哈迈达巴德的谢思·瓦迪拉尔·萨罗巴伊综合医院因多个息肉样肿物出现双侧鼻塞。初步诊断为可能由真菌引起并浸润至鼻腔的鼻息肉病。进行了双侧功能性鼻内镜鼻窦手术及息肉切除术。标本采用标准方法检查,通过玻片培养将真菌鉴定为构巢曲霉。

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