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用于区分食源性病原体沙门氏菌的分子分型方法比较

Comparison of molecular typing methods for the differentiation of Salmonella foodborne pathogens.

作者信息

Foley Steven L, Zhao Shaohua, Walker Robert D

机构信息

National Farm Medicine Center, Marshfield Clinic Research Foundation, Marshfield, Wisconsin 54449, USA.

出版信息

Foodborne Pathog Dis. 2007 Fall;4(3):253-76. doi: 10.1089/fpd.2007.0085.

Abstract

Bacteria belonging to the genus Salmonella are among the leading causes of foodborne disease of bacterial etiology. These bacteria are also widely disseminated throughout the animal kingdom. The ability to identify the food source from which a human pathogen originated would be of great value in reducing the incidence of foodborne disease and the extent of disease outbreaks due to Salmonella. To date, efforts to identify the origin of these pathogens have centered on phenotypic and genotypic characterization of Salmonella isolates. This review focuses molecular or genotypic techniques that are currently being used for typing, and examines their strengths and weaknesses for determining the source of Salmonella foodborne infections.

摘要

沙门氏菌属细菌是细菌性食源性疾病的主要病因之一。这些细菌在整个动物界也广泛传播。确定人类病原体来源的食物来源,对于减少食源性疾病的发病率以及沙门氏菌引起的疾病爆发范围具有重要价值。迄今为止,确定这些病原体来源的努力主要集中在沙门氏菌分离株的表型和基因型特征分析上。本综述重点介绍了目前用于分型的分子或基因技术,并探讨了它们在确定沙门氏菌食源性感染来源方面的优缺点。

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