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希腊的第二性征比例:父亲职业暴露产生影响的证据。

Secondary sex ratio in Greece: evidence of an influence by father's occupational exposure.

作者信息

Alexopoulos Evangelos C, Alamanos Yannis

机构信息

Department of Public Health, Medical School, University of Patras, Patras, Greece.

出版信息

Hum Reprod. 2007 Nov;22(11):2999-3001. doi: 10.1093/humrep/dem309. Epub 2007 Sep 21.

DOI:10.1093/humrep/dem309
PMID:17890723
Abstract

BACKGROUND

Several medical, occupational and environmental paternal exposures have been suggested to be associated with low offspring sex ratios. The purpose of this study was to analyse trends and variations in the secondary sex ratio in Greece during the last 50 years and among different occupational groups of male employees of a shipyard.

METHODS

Data were retrieved from National Statistics Agency databases through the period 1955-2005, and linear regression was administered to examine the evolution of the sex ratio of newborns. In addition, 587 male shipyard employees with 1,012 children were included in the study. Binary logistic regression analysis was conducted to study the influence of father's job title on offspring sex ratio.

RESULTS

Total births in Greece declined by ~30% between the mid 1950s and 1980, while little change in sex ratio occurred. In contrast, while between 1980 and 2000, the birth rate continued to decline at the same rate (by ~30%), there appeared to be a trend toward a decrease in sex ratio. The groups of sandblasters/painters and of ship carpenters showed a significantly lower proportion of boys among newborn children.

CONCLUSIONS

Data from men working in a Greek shipyard suggest that the trend toward a decrease in secondary sex ratio observed in this country may be accounted for by a decrease in male births associated with specific workplace exposures of the father.

摘要

背景

已有研究表明,父亲在医学、职业和环境方面的多种暴露与后代较低的性别比有关。本研究旨在分析希腊过去50年以及一家造船厂男性员工不同职业群体中第二性别比的趋势和变化。

方法

通过检索国家统计局1955 - 2005年期间的数据库获取数据,并采用线性回归分析新生儿性别比的演变。此外,本研究纳入了587名有1012名子女的造船厂男性员工。采用二元逻辑回归分析研究父亲的职称对后代性别比的影响。

结果

20世纪50年代中期至1980年期间,希腊的总出生人数下降了约30%,而性别比变化不大。相比之下,1980年至2000年期间,出生率继续以相同速度下降(约30%),但性别比似乎呈下降趋势。喷砂工/油漆工和船舶木匠组新生儿中男孩的比例明显较低。

结论

来自希腊一家造船厂男性员工的数据表明,该国观察到的第二性别比下降趋势可能是由于父亲在特定工作场所暴露导致男婴出生数量减少所致。

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