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二氧化钍相关的肝脏血管肉瘤

Thorium dioxide-related haemangiosarcoma of the liver.

作者信息

van Kampen R J W, Erdkamp F L G, Peters F P J

机构信息

Department of Internal Medicine, Maasland Hospital, Sittard, the Netherlands.

出版信息

Neth J Med. 2007 Sep;65(8):279-82.

Abstract

Rare tumours of the liver are occasionally seen; thorium dioxide-related haemangiosarcoma of the liver, with an estimated frequency of 0.14 to 0.25 per million in the normal population, is one of these. Causes, epidemiology and pathobiology are described related to a clinical case of angiosarcoma. A differentiation of hepatic tumours with imaging techniques is presented. Last, a short review on up-to-date treatment of haemangiosarcoma is discussed. Lessons can always be learned from history: will the contrast agent gadolinium be the Th232 of this era?

摘要

肝脏的罕见肿瘤偶尔可见;与二氧化钍相关的肝血管肉瘤就是其中之一,在正常人群中估计发病率为百万分之0.14至0.25。本文结合血管肉瘤的一个临床病例描述了其病因、流行病学和病理生物学。介绍了利用成像技术对肝脏肿瘤进行鉴别诊断的方法。最后,讨论了关于血管肉瘤最新治疗方法的简短综述。历史总能给人以教训:造影剂钆会成为这个时代的钍232吗?

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