Donsky Howard, Clarke Don
Dermatology and Cosmetic Center of Rochester, Rochester, NY, USA.
Am J Ther. 2007 Sep-Oct;14(5):442-6. doi: 10.1097/MJT.0b013e31814002c1.
This clinical study was conducted to determine the efficacy and safety of Reliéva cream in adult patients with atopic dermatitis (eczema). This was an open-label trial in 42 patients with atopic dermatitis treated for 12 weeks with Reliéva cream (a homeopathic product containing Psorberine, a proprietary Mahonia aquifolium extract). Efficacy and safety was assessed using Eczema Area and Severity Index scores and a Subject Reported Evaluation of Treatment. The results showed significant (P < 0.05) improvements with respect to Eczema Area and Severity Index scores by comparison to subjects' baseline scores. In addition, subjects responding to a posttreatment evaluation questionnaire indicated a substantial benefit when rating effectiveness, itching, and appearance as a result of using the study preparation. Reliéva cream appears to be a safe and effective treatment for adult patients with atopic dermatitis (eczema).
本临床研究旨在确定Reliéva乳膏对成人特应性皮炎（湿疹）患者的疗效和安全性。这是一项开放标签试验，42例特应性皮炎患者使用Reliéva乳膏（一种含有小檗胺的顺势疗法产品，小檗胺是阔叶十大功劳的专利提取物）治疗12周。使用湿疹面积和严重程度指数评分以及受试者报告的治疗评估来评估疗效和安全性。结果显示，与受试者的基线评分相比，湿疹面积和严重程度指数评分有显著改善（P<0.05）。此外，对治疗后评估问卷做出回应的受试者在对使用研究制剂后的有效性、瘙痒和外观进行评分时表示有很大益处。Reliéva乳膏似乎是治疗成人特应性皮炎（湿疹）的一种安全有效的方法。
