Obara Taku, Ohkubo Takayoshi, Komai Rie, Asayama Kei, Kikuya Masahiro, Metoki Hirohito, Inoue Ryusuke, Murai Kayo, Tanaka Koji, Hashimoto Junichiro, Totsune Kazuhito, Imai Yutaka
Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan.
Blood Press Monit. 2007 Oct;12(5):289-95. doi: 10.1097/MBP.0b013e3282c9ad42.
Recently, it was found that resting heart rate (HR) measured at home (home HR), as well as self-measured blood pressure (BP) at home (home BP), was a strong predictor of the risk of cardiovascular disease mortality in the general Japanese population. It was also reported that home BP levels were not adequately controlled in hypertensive patients. Little information, however, is available on the current status of home HR control in treated patients with hypertension. The objective of this study was to examine the current status of home HR control and home BP control among treated patients with hypertension.
Home HR and BP were measured using a self-monitored BP measuring device. Morning home HR and BP were obtained in 3183 patients and evening home HR and BP were obtained in 3106 patients. On the basis of an earlier study, we defined a home HR value of >or=70 beats/min as 'high home HR'.
The mean home HR value was 67.2+/-9.1 beats/min in the morning and 69.6+/-9.2 beats/min in the evening. Of the 3183 patients, 35.7% had a high home HR in the morning and 46.7% of the 3106 patients had a high home HR in the evening. The prevalence of patients with a high home HR and a controlled home BP (<135/85 mmHg) was 11.3% in the morning and 24.2% in the evening.
Resting home HR control and home BP control were inadequate.
最近发现，在家测量的静息心率（HR）以及在家自测血压（BP）是日本普通人群心血管疾病死亡风险的有力预测指标。也有报道称高血压患者的家庭血压水平未得到充分控制。然而，关于接受治疗的高血压患者家庭心率控制的现状，目前几乎没有相关信息。本研究的目的是调查接受治疗的高血压患者家庭心率控制和家庭血压控制的现状。
使用自我监测血压测量设备测量家庭心率和血压。在3183例患者中获取了早晨的家庭心率和血压，在3106例患者中获取了晚上的家庭心率和血压。根据早期研究，我们将家庭心率值≥70次/分钟定义为“高家庭心率”。
早晨家庭心率的平均值为67.2±9.1次/分钟，晚上为69.6±9.2次/分钟。在3183例患者中，35.7%的患者早晨家庭心率较高，在3106例患者中，46.7%的患者晚上家庭心率较高。家庭心率高且家庭血压得到控制（<135/85 mmHg）的患者患病率，早晨为11.3%，晚上为24.2%。
静息家庭心率控制和家庭血压控制不足。
