Tsujikawa Akitaka, Hirami Yasuhiko, Nakanishi Hideo, Ojima Yumiko, Aikawa Hiroko, Tamura Hiroshi, Otani Atsushi, Yoshimura Nagahisa
Department of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Retina. 2007 Sep;27(7):832-8. doi: 10.1097/IAE.0b013e318150d864.
To study the clinical characteristics of tears of the retinal pigment epithelium (RPE) in eyes with polypoidal choroidal vasculopathy (PCV).
The authors report eight eyes of eight patients with PCV that had tears of the RPE. These were examined with angiography and tomography.
Eight eyes of eight patients (seven men and one woman) had RPE tears at the margin of a serosanguineous pigment epithelial detachment (PED) associated with PCV. Tears of the RPE were detected at the initial visit in one eye and during follow-up without any treatment in five eyes. In two eyes, the RPE tears were detected 3 months and 6 months, respectively, after photodynamic therapy. In all eyes, the RPE tears were detected at the side opposite to the polypoidal lesions of the PEDs, and the fovea was not involved in the RPE tear. Visual acuity in the seven eyes without RPE tears on presentation ranged from 20/100 to 20/16 (median, 20/32). During follow-up, three of these eyes lost three or more lines of vision. At the final examination, while three of these eyes had visual acuity of 20/25 or better, the other four had visual acuity of 20/200 or worse.
In eyes with PCV, RPE tears can occur at the margin of serosanguineous PEDs-either spontaneously or after photodynamic therapy.
研究息肉状脉络膜血管病变（PCV）患者视网膜色素上皮（RPE）撕裂的临床特征。
作者报告了8例PCV患者的8只眼出现了RPE撕裂。对这些眼睛进行了血管造影和断层扫描检查。
8例患者（7男1女）的8只眼在与PCV相关的浆液性色素上皮脱离（PED）边缘出现RPE撕裂。1只眼在初次就诊时发现RPE撕裂，5只眼在随访期间未接受任何治疗的情况下发现RPE撕裂。2只眼分别在光动力治疗后3个月和6个月发现RPE撕裂。在所有眼中，RPE撕裂均出现在PED息肉样病变的对侧，且黄斑未累及RPE撕裂。初次就诊时7只无RPE撕裂眼的视力范围为20/100至20/16（中位数，20/32）。随访期间，其中3只眼视力下降了3行或更多。在最后检查时，其中3只眼视力为20/25或更好，而另外4只眼视力为20/200或更差。
在PCV患者眼中，RPE撕裂可发生在浆液性PED边缘——自发出现或在光动力治疗后出现。
