Qiao L, Ma L T, Min J M, Zhang L H
School of Pharmaceutical Sciences, Beijing Medical University.
Yao Xue Xue Bao. 1991;26(6):420-5.
The derivatives of 5'-dehydroxymethyl carbocyclic nucleoside were synthesized by condensation of cyclopentenyl chloride and corresponding pyrimidines followed by epoxidation and substitution. All compounds were screened for anticancer and antiviral activities and no activity was found.
5'-去羟甲基碳环核苷的衍生物通过环戊烯基氯与相应嘧啶缩合，随后进行环氧化和取代反应合成。对所有化合物进行了抗癌和抗病毒活性筛选，未发现活性。
