Lin L M, Zhang N J, Wang H Y
Weifang Institute for Drug Control.
Yao Xue Xue Bao. 1991;26(6):451-7.
This paper provides the basic principle and experimental technique of differential--linear combination equal value derivative spectrophotometry. Quantitative analysis of three or four component--mixture can be done without separation. This method was investigated to assay the contents of chlorphenamine and propantheline bromide in Pukeling tablets by using UV-210A spectrophotometer. The average recoveries of chlorphenamine and propantheline bromide were 100.2 +/- 1.49% (CV) and 99.89 +/- 1.03% (CV) respectively. The results showed that it not only can effectively remove disturbances from each other, but also give higher sensitivity and accuracy.
本文介绍了差示线性组合等价值导数分光光度法的基本原理和实验技术。无需分离即可对三组分或四组分混合物进行定量分析。采用UV - 210A分光光度计研究了该方法用于测定扑咳灵片中氯苯那敏和溴丙胺太林含量。氯苯那敏和溴丙胺太林的平均回收率分别为100.2±1.49%（变异系数）和99.89±1.03%（变异系数）。结果表明，该方法不仅能有效消除相互干扰，而且具有较高的灵敏度和准确性。
