Rygaard K, Møller M, Henriksen O
Institute of Medical Anatomy, University of Copenhagen, Denmark.
Acta Physiol Scand Suppl. 1991;603:115-8.
Previous studies with the local 133Xenon washout method of the local regulation of blood flow in peripheral tissues in man gave evidence for a local veno-arteriolar sympathetic axon reflex which constricts arterioles when the venous transmural pressure is increased 25 mm Hg or more. The present study with the formaldehyde induced histofluorescence technique applied to skeletal muscle biopsies from dogs showed a dense plexus of noradrenergic sympathetic fibers around arterioles. Venules were generally devoid of these fibers. In certain instances sympathetic fibers left the arteriolar network to innervate the concomitant venule directly. Some of these fibers could be seen returning from the venule back to the arteriolar network. We suggest that the adrenergic fibers derived from the sympathetic plexus around the arterioles who innervate the venules can be the anatomical substrate for the local veno-arteriolar sympathetic axon reflex.
以往采用局部133氙洗脱法对人体外周组织局部血流调节进行的研究表明，存在一种局部静脉 - 小动脉交感神经轴突反射，当静脉跨壁压升高25毫米汞柱或更多时，该反射会使小动脉收缩。本研究采用甲醛诱导组织荧光技术对犬的骨骼肌活检样本进行检测，结果显示小动脉周围有密集的去甲肾上腺素能交感神经纤维丛。小静脉通常没有这些纤维。在某些情况下，交感神经纤维离开小动脉网络，直接支配与之相伴的小静脉。可以看到其中一些纤维从小静脉返回小动脉网络。我们认为，来自小动脉周围交感神经丛、支配小静脉的肾上腺素能纤维可能是局部静脉 - 小动脉交感神经轴突反射的解剖学基础。
