果蝇中江氏器的发育
Development of Johnston's organ in Drosophila.
作者信息
Eberl Daniel F, Boekhoff-Falk Grace
机构信息
Department of Biology, University of Iowa, Iowa City, IA 52242-1324, USA.
出版信息
Int J Dev Biol. 2007;51(6-7):679-87. doi: 10.1387/ijdb.072364de.
Abstract
Hearing is a specialized mechanosensory modality that is refined during evolution to meet the particular requirements of different organisms. In the fruitfly, Drosophila, hearing is mediated by Johnston's organ, a large chordotonal organ in the antenna that is exquisitely sensitive to the near-field acoustic signal of courtship songs generated by male wing vibration. We summarize recent progress in understanding the molecular genetic determinants of Johnston's organ development and discuss surprising differences from other chordotonal organs that likely facilitate hearing. We outline novel discoveries of active processes that generate motion of the antenna for acute sensitivity to the stimulus. Finally, we discuss further research directions that would probe remaining questions in understanding Johnston's organ development, function and evolution.
摘要
听觉是一种特殊的机械感觉模态，在进化过程中不断完善，以满足不同生物体的特定需求。在果蝇中，听觉由约翰斯顿器官介导，它是触角中的一个大型弦音器官，对雄性翅膀振动产生的求偶歌曲的近场声学信号极为敏感。我们总结了在理解约翰斯顿器官发育的分子遗传决定因素方面的最新进展，并讨论了与其他弦音器官惊人的差异，这些差异可能有助于听觉。我们概述了产生触角运动以对刺激产生敏锐敏感性的主动过程的新发现。最后，我们讨论了进一步的研究方向，这些方向将探索在理解约翰斯顿器官发育、功能和进化方面仍然存在的问题。
相似文献
1
Development of Johnston's organ in Drosophila.果蝇中江氏器的发育
Int J Dev Biol. 2007;51(6-7):679-87. doi: 10.1387/ijdb.072364de.
2
Towards a molecular understanding of Drosophila hearing.迈向对果蝇听觉的分子理解。
J Neurobiol. 2002 Nov 5;53(2):172-89. doi: 10.1002/neu.10126.
3
Hearing in Drosophila: development of Johnston's organ and emerging parallels to vertebrate ear development.果蝇的听觉：江氏器官的发育以及与脊椎动物耳发育新出现的相似之处。
Dev Dyn. 2005 Mar;232(3):550-8. doi: 10.1002/dvdy.20207.
4
Anatomical and molecular design of the Drosophila antenna as a flagellar auditory organ.果蝇触角作为鞭毛听觉器官的解剖学和分子设计。
Microsc Res Tech. 2004 Apr 15;63(6):388-99. doi: 10.1002/jemt.20053.
5
Distinct sensory representations of wind and near-field sound in the Drosophila brain.果蝇大脑中对风和近场声音的不同感觉表征。
Nature. 2009 Mar 12;458(7235):201-5. doi: 10.1038/nature07843.
6
Mechanoreceptors in insects: Johnston's organ in Nezara viridula (L) (Pentatomidae, Heteroptera).昆虫中的机械感受器：绿蝽（Nezara viridula (L)）（蝽科，半翅目）中的江氏器
Pflugers Arch. 1996;431(6 Suppl 2):R281-2. doi: 10.1007/BF02346378.
7
Antennal hearing in insects--new findings, new questions.昆虫的触角听觉——新发现，新问题。
Hear Res. 2011 Mar;273(1-2):7-13. doi: 10.1016/j.heares.2010.03.092. Epub 2010 Apr 27.
8
Encoding properties of the mechanosensory neurons in the Johnston's organ of the hawk moth, Manduca sexta.烟草天蛾（Manduca sexta）触角感受器约翰斯顿氏器官中机械感觉神经元的编码特性。
J Exp Biol. 2014 Sep 1;217(Pt 17):3045-56. doi: 10.1242/jeb.101568. Epub 2014 Jun 19.
9
Distinct subpopulations of mechanosensory chordotonal organ neurons elicit grooming of the fruit fly antennae.机械敏感的琴状感觉器官神经元的不同亚群引起果蝇触角的梳理。
Elife. 2020 Oct 26;9:e59976. doi: 10.7554/eLife.59976.
10
Feeling the vibes: chordotonal mechanisms in insect hearing.感受振动：昆虫听觉中的弦音感受器机制
Curr Opin Neurobiol. 1999 Aug;9(4):389-93. doi: 10.1016/S0959-4388(99)80058-0.
引用本文的文献
1
A function of Spalt proteins in heterochromatin organization and maintenance of genomic DNA integrity.Spalt蛋白在异染色质组织和基因组DNA完整性维持中的作用。
Development. 2025 May 15;152(10). doi: 10.1242/dev.204258. Epub 2025 May 16.
2
Preclinical Models to Study the Molecular Pathophysiology of Meniere's Disease: A Pathway to Gene Therapy.用于研究梅尼埃病分子病理生理学的临床前模型：基因治疗的途径
J Clin Med. 2025 Feb 20;14(5):1427. doi: 10.3390/jcm14051427.
3
A nonneural miRNA cluster mediates hearing via repression of two neural targets.一个非神经 miRNA 簇通过抑制两个神经靶标来介导听力。
Genes Dev. 2023 Dec 26;37(21-24):1041-1051. doi: 10.1101/gad.351052.123.
4
Central projections from Johnston's organ in the locust: Axogenesis and brain neuroarchitecture.蝗虫中约翰斯顿器官的中枢投射：轴突发生和脑神经结构。
Dev Genes Evol. 2023 Dec;233(2):147-159. doi: 10.1007/s00427-023-00710-0. Epub 2023 Sep 11.
5
The auditory efferent system in mosquitoes.蚊子的听觉传出系统。
Front Cell Dev Biol. 2023 Feb 27;11:1123738. doi: 10.3389/fcell.2023.1123738. eCollection 2023.
6
Early embryonic development of Johnston's organ in the antenna of the desert locust Schistocerca gregaria.约翰斯顿氏器在沙漠蝗触角中的早期胚胎发育。
Dev Genes Evol. 2022 Dec;232(5-6):103-113. doi: 10.1007/s00427-022-00695-2. Epub 2022 Sep 23.
7
Chasing Flies: The Use of Wingbeat Frequency as a Communication Cue in Calyptrate Flies (Diptera: Calyptratae).追逐苍蝇：翅振频率作为有瓣蝇类（双翅目：有瓣蝇类）交流线索的应用
Insects. 2022 Sep 9;13(9):822. doi: 10.3390/insects13090822.
8
Charging Up the Periphery: Glial Ionic Regulation in Sensory Perception.为外周充电：感觉感知中的胶质细胞离子调节
Front Cell Dev Biol. 2021 Aug 11;9:687732. doi: 10.3389/fcell.2021.687732. eCollection 2021.
9
Mechanosensory neuron regeneration in adult .成年. 中的机械感觉神经元再生。
Development. 2021 Mar 10;148(5):dev187534. doi: 10.1242/dev.187534.
10
Identification of genomic enhancers through spatial integration of single-cell transcriptomics and epigenomics.通过单细胞转录组学和表观基因组学的空间整合来鉴定基因组增强子。
Mol Syst Biol. 2020 May;16(5):e9438. doi: 10.15252/msb.20209438.
本文引用的文献
1
The thoracico-abdominal nervous system of an adult insect, Drosophila melanogaster.成年昆虫黑腹果蝇的胸腹神经系统。
J Comp Neurol. 1948 Jun;88(3):347-409. doi: 10.1002/cne.900880303.
2
Cut mutant Drosophila auditory organs differentiate abnormally and degenerate.切割突变体果蝇的听觉器官分化异常并退化。
Fly (Austin). 2007 Mar-Apr;1(2):86-94. doi: 10.4161/fly.4242.
3
Dynamic range compression in the honey bee auditory system toward waggle dance sounds.蜜蜂听觉系统对摇摆舞声音的动态范围压缩。
PLoS One. 2007 Feb 21;2(2):e234. doi: 10.1371/journal.pone.0000234.
4
Functional dissection of the neural substrates for gravitaxic maze behavior in Drosophila melanogaster.果蝇重力迷宫行为神经基质的功能剖析。
J Comp Neurol. 2007 Apr 10;501(5):756-64. doi: 10.1002/cne.21257.
5
Nonlinear auditory mechanism enhances female sounds for male mosquitoes.非线性听觉机制增强了雄性蚊子对雌性声音的感知。
Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16734-9. doi: 10.1073/pnas.0606319103. Epub 2006 Oct 26.
6
Comprehensive classification of the auditory sensory projections in the brain of the fruit fly Drosophila melanogaster.果蝇黑腹果蝇大脑中听觉感觉投射的综合分类。
J Comp Neurol. 2006 Nov 20;499(3):317-56. doi: 10.1002/cne.21075.
7
Free-flight responses of Drosophila melanogaster to attractive odors.黑腹果蝇对有吸引力气味的自由飞行反应。
J Exp Biol. 2006 Aug;209(Pt 15):3001-17. doi: 10.1242/jeb.02305.
8
Flying in tune: sexual recognition in mosquitoes.合拍飞行：蚊子的性别识别
Curr Biol. 2006 Jul 11;16(13):1311-6. doi: 10.1016/j.cub.2006.05.053.
9
Specification of auditory sensitivity by Drosophila TRP channels.果蝇TRP通道对听觉敏感性的调控
Nat Neurosci. 2006 Aug;9(8):999-1000. doi: 10.1038/nn1735. Epub 2006 Jul 2.
10
Gravitaxis in Drosophila melanogaster: a forward genetic screen.黑腹果蝇的重力趋向性：一项正向遗传学筛选。
Genes Brain Behav. 2006 Apr;5(3):222-39. doi: 10.1111/j.1601-183X.2005.00154.x.
Zotero 插件