哺乳动物细胞的白血病病毒感染：对两种“转化相关”表面特性的影响。
Leukemia virus infection of mammalian cells: effect on two "transformation-associated" surface properties.
作者信息
Noonan K D, Wright P J, Bouck N, Di Mayorca G
出版信息
J Virol. 1976 Jun;18(3):1134-8. doi: 10.1128/JVI.18.3.1134-1138.1976.
Abstract
We demonstrated that the productive infection of three different mammalian cell lines with two separate leukemia viruses is sufficient to induce a change in surface architecture that may be detected as enhanced agglutinability with two different plant lectins. Subsequent transformation of one of these cell lines with a chemical carcinogen did not further modify the agglutinability of the cell lines. Using a polyoma virus-transformed derivative of one of the parental lines, we have demonstrated that the LETS protein (whose absence from the surface membrane has been considered a marker of the transformed phenotype) may be present in cells displaying the capacity to plate in soft agar.
摘要
我们证明，两种不同的白血病病毒对三种不同的哺乳动物细胞系进行有效感染，足以诱导细胞表面结构发生变化，这种变化可表现为对两种不同植物凝集素的凝集性增强。随后用化学致癌物对其中一个细胞系进行转化，并未进一步改变这些细胞系的凝集性。利用亲本细胞系之一的多瘤病毒转化衍生物，我们证明，LETS蛋白（其在细胞膜表面的缺失被认为是转化表型的一个标志）可能存在于具有在软琼脂中铺板能力的细胞中。
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2
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3
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